Your immune system is more than just a line of defence. It’s a complex network that protects your body from everyday stressors, pathogens, and inflammation. And while balanced nutrition, sleep, and exercise remain essential, modern life often challenges our ability to maintain consistent immune health. 

That’s where daily superfood powders like AEON ONE™ and AG1® (Athletic Greens) come in. Both promise to deliver comprehensive nutrient support designed to strengthen immunity, improve recovery, and enhance overall vitality. 

But while AG1® focuses on being a science-formulated foundational nutrition system, AEON ONE™ emphasizes a whole-food, nature-first approach, blending fruits, greens, mushrooms, adaptogens, and probiotics to build resilience from the inside out. 

So, let’s explore how each supports immune function through different nutritional philosophies. 

Why Immune Support Begins with Nutrition 

The Immune System as an Ecosystem 

Your immune system is interconnected with nearly every process in your body. It’s influenced by diet, sleep, stress, gut health, and even hydration. Nutritional deficiencies, chronic stress, and poor digestion can weaken immune defences, leaving you more vulnerable to infections or fatigue. 

The Gut-Immune Connection 

About 70% of your immune cells reside in the gut, specifically in what’s called the gut-associated lymphoid tissue (GALT). This means your digestive health directly impacts how well your immune system functions. Probiotics, prebiotics, and digestive enzymes play a key role in maintaining a balanced microbiome, which acts as your first line of defence against harmful bacteria and toxins. 

The Role of Antioxidants and Adaptogens 

Antioxidants may help neutralize free radicals that cause oxidative stress, a major factor in immune decline. Adaptogens such as ashwagandha and rhodiola can help regulate cortisol, the stress hormone that can suppress immune activity when elevated for too long. 

The Whole-Food Advantage 

While isolated vitamins can support immunity, whole-food super blends offer something more; they combine vitamins, phytonutrients, fibres, and enzymes that work synergistically. This allows for better absorption and utilization by the body. 

AEON ONE™: Whole-Food Synergy for Immunity and Resilience 

Brand Philosophy 

AEON ONE™ takes a holistic approach to immune health. Built entirely from whole-food ingredients, it provides antioxidants, phytonutrients, adaptogens, and probiotics in one scoop. True Aeon calls it “Made by nature, not in a lab” a philosophy rooted in balance, not excess. 

Unlike supplements that focus only on vitamins, AEON ONE™ builds a foundation for immunity through gut health, stress regulation, and cellular nourishment. 

Key Immune-Supporting Ingredients 

1. Functional Mushrooms 

 AEON ONE™ includes eight immune-modulating mushrooms, each offering unique bioactive compounds: 

• Reishi: Supports immune balance and supports a healthy inflammatory response. 
• Chaga: Rich in beta-glucans and antioxidants that support cell repair. 
• Lion’s Mane: Enhances nerve growth and may modulate immune function through gut-brain signalling. 
• Cordyceps: Improves oxygen utilization and endurance, supporting energy metabolism during immune challenges. 
• Turkey Tail, Shiitake, Maitake, Agaricus Blazei: Known for polysaccharides and beta-glucans that activate natural killer (NK) cells and macrophages, key immune defenders. 

These mushrooms help maintain immune balance, supporting both defence and recovery. 

2. Adaptogens for Immune Resilience 

 Chronic stress weakens immunity by elevating cortisol, which suppresses immune cell activity. AEON ONE™ integrates ashwagandha, rhodiola, maca, and ginseng, which have been studied for their ability to: 

• Reduce cortisol levels. 
• Increase physical and mental resilience. 
• Support recovery from fatigue and stress-related immune suppression. 

Adaptogens make AEON ONE™ stand out because they strengthen the mind-body connection, allowing your body to maintain immune balance even under pressure. 

3. Antioxidant-Rich Fruits and Greens 

 The blend of red, purple, and green superfoods delivers a wide spectrum of antioxidants and phytonutrients: 

• Acerola cherry, pomegranate, and berries provide vitamin C and polyphenols. 
• Spinach, spirulina, chlorella, moringa, and wheatgrass supply chlorophyll, magnesium, and iron essential for immune cell production. 
• Turmeric and ginger add anti-inflammatory compounds (curcumin and gingerols) that reduce chronic inflammation and support a healthy immune response. 

These ingredients don’t just feed the immune system; they protect it from oxidative stress and promote overall cellular repair. 

4. Probiotics and Digestive Enzymes 

 AEON ONE™ uses Bacillus coagulans, a spore-forming probiotic that survives stomach acid and colonizes the intestines effectively. This strains report improvements in digestive comfort, microbial balance, and immune signaling in specific populations. Paired with digestive enzymes and natural prebiotic fibres from fruits and greens, AEON ONE™ ensures optimal nutrient absorption and a thriving microbiome your internal immune shield. 

5. Electrolytes and Hydration Support 

 Hydration plays a surprisingly important role in immune efficiency. AEON ONE™ includes coconut water powder and Himalayan pink salt, which provide natural electrolytes and trace minerals. These help maintain cellular hydration and support immune cell communication throughout the body. 

How AEON ONE™ Strengthens Immunity Holistically 

AEON ONE™ works on multiple levels: 

• Strengthens the gut barrier to prevent pathogen infiltration. 
• Reduces oxidative and inflammatory stress with antioxidants. 
• Enhances adaptive stress response through adaptogens. 
• Balances immune activation through mushrooms and micronutrients. 

This multi-layered approach supports both immediate immune defences and long-term resilience. 

Format, Taste, and Price 

• Format: Powder, mixable in water or smoothies. 
• Flavour: Fruity and berry-forward with subtle earthy tones. 
• Serving Size: 30 servings per container. 
• Price: $119.95 regular / $89.95 sale ($3.00 per serving).* 

For many users, AEON ONE™’s all-in-one design may reduce the need for separate greens, probiotic, enzyme, or mushroom supplements; though individual supplement needs vary. 

*At the time of review (September 2025), the retail price on the brand’s official site was $119.95 ($89.95 on sale) for 30 servings of AEON ONE™ (TrueAeon.com, accessed Sept 30, 2025). 

AG1®: Science-Formulated Immune Support 

Brand Philosophy 

AG1® positions itself as a foundational nutrition formula that delivers everything your body needs for baseline health. Its immune-support strategy is built on micronutrient optimization, filling dietary gaps that can compromise immune function. 

It’s marketed as a performance-focused product for athletes, busy professionals, and health-conscious individuals who want an easy, science-backed daily ritual. 

Key Immune-Supporting Ingredients 

1. Vitamins and Minerals 

 AG1® provides a robust line up of immune-essential micronutrients: 

• Vitamin C from acerola and ascorbic acid. 
• Vitamin A, E, and K2 for cellular integrity and immune cell signalling. 
• Zinc, Selenium, and Copper for antioxidant defence and immune enzyme activity. 

These vitamins are crucial for the formation and function of white blood cells, the backbone of immune defence. 

2. Probiotics and Prebiotics 

AG1® lists five probiotic strains (e.g., Lactobacillus acidophilus, Bifidobacterium bifidum) on its label (drinkag1.com, accessed September 2025). Non-spore-forming strains may require careful formulation and storage to maintain efficacy 

3. Superfoods and Extracts 

 The greens blend in AG1® features spirulina, chlorella, wheatgrass, and barley leaf powder, providing antioxidants and micronutrients. It also includes citrus bioflavonoids, milk thistle, and green tea extract, which add further antioxidant support. 

These compounds protect immune cells from oxidative stress and may enhance liver detoxification, an important secondary defence system. 

4. Adaptogens and Botanicals 

 AG1® includes a few adaptogens, such as ashwagandha and rhodiola, though at smaller concentrations compared to AEON ONE™. These support energy balance and mild stress resilience, but are not a central part of the formulation. 

How AG1® Supports Immune Function 

AG1®’s immune benefits stem primarily from micronutrient optimization and gut support. Ensuring the body gets consistent levels of vitamins, minerals, and antioxidants, helps immune cells function efficiently. 

However, its lack of hydration support, stress-regulating adaptogens, and multiple mushroom species means it operates more as a nutritional insurance policy than a full spectrum immune modulator. 

Format, Taste, and Price 

• Format: Powder (mix with water). 
• Flavour: Mild and grassy with tropical undertones. 
• Serving Size: 30 servings per pouch. 
• Price: $99 one-time / $79 subscription ($2.63–$3.30 per serving).

**At the time of review (September 2025), AG1® was listed for $99 for 30 servings (drinkag1.com, accessed Sept 30, 2025).  

AEON ONE™ vs AG1®: Side-by-Side Immune Support Comparison 

*At the time of review (September 2025), the retail price on the brand’s official site was $119.95 ($89.95 on sale) for 30 servings of AEON ONE™ (TrueAeon.com, accessed Sept 30, 2025). 

**At the time of review (September 2025), AG1® was listed for $99 for 30 servings (drinkag1.com, accessed Sept 30, 2025).  

Supplement Safety Reminder  

The supplement industry is loosely regulated, and not all marketing claims are independently verified. To ensure you’re making an informed choice: 

• Read product labels carefully 
• Look for third-party testing or certifications 
• Consult a healthcare professional before starting new supplements 

Also Read: AEON ONE™ vs AG1®: Which Superfood Blend Offers Better Daily Nutrition?

Which Supports Immunity More Effectively? 

AG1® Strengths 

• Provides strong vitamin and mineral coverage to fill dietary gaps. 
• Offers a robust enzyme and probiotic system for digestive-immune balance. 
• Ideal for individuals looking for a simple, science-backed foundational supplement. 

AEON ONE™ Strengths 

• Delivers deeper immune modulation through mushrooms, adaptogens, and antioxidants. 
• Addresses stress-related immune suppression and inflammation simultaneously. 
• Includes hydration support and gut-brain synergy for total-body balance. 
• Provides both immediate defence and long-term resilience. 

The Verdict 

Both supplements strengthen immune function but serve different audiences: 

• AG1® focuses on nutrient coverage and maintenance. 
• AEON ONE™ builds resilience and adaptive strength through nature-based synergy. 

If you want a science-formulated foundation for general wellness, AG1® fits the bill. But if you want to actively fortify your immune system through whole-food, adaptogen, and mushroom synergy, AEON ONE™ may have the edge. 

Also Read:  AEON ONE™ vs AG1® (Athletic Greens): Which Superfood Blend Delivers More Broad-Spectrum Nutrition? 

Conclusion 

Your immune system is not just a shield that fights off germs - it’s a highly intelligent network that depends on balance, nourishment, and recovery. The foods and supplements you consume can either strengthen that system or leave it vulnerable. 

Both AEON ONE™ and AG1® were designed with the same goal: to make it easier to support your immune system daily. But they take very different paths to get there. 

AG1® represents a science-formulated approach. It’s built on a foundation of vitamins, minerals, and probiotics to cover the essentials. Its strength lies in providing consistent micronutrient support and digestive balance through multi-strain probiotics and enzymes. For people who want simplicity, efficiency, and a research-backed baseline for wellness, AG1® delivers exactly that. 

AEON ONE™, however, takes the idea of immune support further. It approaches immunity as part of a whole-body ecosystem rather than an isolated function.  

By combining eight functional mushrooms, multiple adaptogens, antioxidants, probiotics, and hydration support, it helps your body not only defend itself but also adapt, recover, and build resilience.  

It doesn’t just fill nutritional gaps - it supports the connection between your gut, brain, and immune system, helping you perform and feel your best even under stress. 

While AG1® offers strength in structure and scientific precision, AEON ONE™ offers strength in synergy. Its whole-food, nature-first composition provides broader benefits, supporting immune function through antioxidant protection, microbiome health, and stress regulation. 

If you want a convenient greens-based powder that covers essential nutrition, AG1® is a solid choice. But if your goal is comprehensive, adaptive immune support that works with your body’s natural systems - not just against illness - AEON ONE™ may have the edge. 

In a world where the immune system is constantly challenged by stress, environmental toxins, and poor diets, AEON ONE™ offers a daily ritual rooted in what truly matters: restoring balance through nature’s most powerful ingredients. 

Regulatory Caution: dietary supplement claims are not evaluated by the FDA the same way drugs are, and brands have faced regulatory scrutiny in the past for overstated health claims. Always check product Supplement Facts, third party test results, and consult a healthcare professional before starting new supplements. Look for third party testing and certificates of analysis when assessing quality. 

FAQ 

Does AEON ONE™ contain vitamin C and zinc? 

Yes. AEON ONE™ contains vitamin C naturally from fruits like acerola cherry and pomegranate, along with zinc and trace minerals from its greens and sea buckthorn blend. 

Does AG1® contain mushrooms? 

AG1® includes a mushroom blend on some formulations—check the specific product label in use (source: drinkag1.com). 

Which is better for stress-related immune issues? 

AEON ONE™ includes adaptogens like ashwagandha and rhodiola that support stress balance and cortisol regulation, giving it an advantage in stress-related immunity. 

Which product supports gut-immune balance better? 

Both contain probiotics, but AEON ONE™ adds enzymes, prebiotic fibres, and hydration support that further optimize gut-immune communication. 

Can you take both AEON ONE™ and AG1® together? 

You can, but it’s not necessary. Both overlap in function. AEON ONE™ alone provides broader coverage for immune health and stress resilience. 

Are supplement claims regulated? 

Not in the same way as medications. Supplements fall under food regulation, which means companies can market them with limited oversight. Because of this, it’s best to check for transparent ingredient lists, third-party testing, and to consult your healthcare provider before use.